Krupig, B., Hedley, A. and Murphy, D. (2018) RNA-seq to investigate impact of treatment of KRAS mutant NCI-H2009 lung adenocarcinoma cells with the multi-ERBB inhibitor Neratinib. [Data Collection]

Collection description

KRAS mutation is widely presumed to confer independence from upstream RTK signalling, however emerging evidence from mouse models of lung cancer suggests that ERBB RTKs may amplify signalling through RAS isoforms and participate in mutant RAS-driven lung cancer. This is one of 3 datasets where we examined the transcriptional impact of treatment of KRAS mutant human lung cancer cell lines with the multi-ERBB inhibitor Neratinib

College / School:	College of Medical Veterinary and Life Sciences > School of Cancer Sciences
Date Deposited:	28 Mar 2019 12:22
URI:	https://researchdata.gla.ac.uk/id/eprint/770
Additional details Additional details Dataset URL: https://www.ebi.ac.uk/arrayexpress/experiments/E-MTAB-6486/ Type of data: Other Date: 1 June 2018 Date type: Publication Additional information: This is a metadata-only record. To access the data associated with this record, please follow the link provided to ArrayExpress, record accession E-MTAB-6486 Resource language: English Status: Published Data Publisher: ArrayExpress Last Modified: 28 Mar 2019 12:22

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