McGonigal, R. , Cunningham, M. , Smyth, D., Chou, M., Barrie, J., Wilkie, A., Campbell, C., Saatman, K. E., Lunn, M. and Willison, H. (2022) The endogenous calpain inhibitor calpastatin attenuates axon degeneration in murine Guillain-Barré syndrome. [Data Collection]

Collection description

Study Aim: This study used established ex and in vivo acute and subacute mouse models of axonal Guillain-Barre syndrome (GBS)(AMAN) to study the therapeutic advantages of calpain inhibition to protect axon integrity and recovery.

Images were captured using Zeiss LSM or Zeiss AxioImager Z1 microscopes and observed using Zeiss Zen or ImageJ (FIJI) software. Quantification was performed using the same. Analysis output can be found in Excel sheets. Statistical analysis was performed using GraphPad software.

Funding:	Wellcome Trust (WELLCOTR) [092805/Z/10/Z] Wellcome Trust (WELLCOTR) [202789/Z/16/Z]
College / School:	College of Medical Veterinary and Life Sciences > School of Infection and Immunity
Date Deposited:	29 Nov 2022 15:27
URI:	https://researchdata.gla.ac.uk/id/eprint/1360
Additional details Additional details Type of data: Spreadsheet, Text Collection period: From To 2017 2022 Date: 29 November 2022 Resource language: EN Status: Published Data Publisher: University of Glasgow Copyright holders: University of Glasgow Last Modified: 01 Dec 2022 10:52

Available Files

Data

1360.zip 1360.zip 1360.zip Visible to: Anyone Content type: Data Metadata Revision: 2 Mime-Type: application/zip License: Creative Commons: Attribution 4.0 File size: 821kB

Read me

Readme_Calpain_paper.docx Readme_Calpain_paper.docx Readme_Calpain_paper.docx Visible to: Anyone Content type: Read me Metadata Revision: 2 Mime-Type: application/vnd.openxmlformats-officedocument.wordprocessingml.document License: Creative Commons: Attribution 4.0 File size: 26kB

Repository Staff Only: Update this record