Combined colorectal cancer array

Edwards, J. and Powel, A. (2019) Combined colorectal cancer array. [Data Collection]

Collection description

This database was established to allow us to investigate biomarkers in colorectal cancer.

Safehaven number: GSH/18/ON007

Contains 1030 patients who had undergone a potentially curative resection for stage I-IV CRC between 1997 and 2007 at the Glasgow Royal Infirmary, Western Infirmary or Stobhill Hospitals (Glasgow, UK). Resection was considered curative based on pre-operative computed tomography and intra-operative findings. Tumours were staged using the fifth edition of the AJCC/UICC-TNM staging system. The presence of venous invasion was assessed using elastica staining and Ki67 proliferation index was previously established in this cohort. Tumour differentiation, graded as well/moderate or poor in accordance with Royal College of Pathologists and additional data were taken from pathology reports issued following resection. Following surgery, patients with stage III or high-risk stage II disease and without significant co-morbid disease precluding adjuvant treatment were considered for 5-fluorouracil-based chemotherapy. Patients were followed up for at least five years and date and cause of death were crosschecked with the cancer registration system and the Registrar General (Scotland). Cancer-specific survival (CSS) was measured from date of surgery until date of death from CRC.

College / School: College of Medical Veterinary and Life Sciences > School of Cancer Sciences
Date Deposited: 15 Apr 2019 11:19

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Edwards, J. and Powel, A. (2019); Combined colorectal cancer array

NHS Greater Glasgow and Clyde Safehaven

Retrieved: 2024-04-20