Leslie, H. and Hatthakarnkul, P. (2022) Spatial transcriptomic analysis of tumoural (PanCK+) and stromal (PanCK-) regions in TNBC tissue samples using an immunoncology probe-based panel on the GeoMx™ Digital Spatial Profiler (DSP). [Data Collection]

Collection description

This dataset was obtained by in-situ hybridisation of probes to a tissue microarray (TMA) of human triple-negative breast cancer (TNBC) tissue. The purpose of this dataset is to allow interrogation of the differential transcriptomic profiles of tumoural (PanCK+) and stromal (PanCK-) regions of TNBC disease to further investigate disease pathogenesis and spark hypothesis-driven research into potential new therapies and prognostic markers for patients with this subtype of disease.

College / School:	College of Medical Veterinary and Life Sciences > School of Cancer Sciences
Date Deposited:	15 Aug 2022 13:24
URI:	https://researchdata.gla.ac.uk/id/eprint/1333
Additional details Additional details Type of data: Image, Spreadsheet, Text Collection period: From To 4 May 2021 20 May 2021 Date: 15 August 2022 Date type: Publication Additional information: Funding acknowledged from NHS Greater Glasgow and Clyde Breast Endowment Fund Resource language: EN Status: Published Data Publisher: University of Glasgow Copyright holders: University of Glasgow Last Modified: 25 Jan 2024 09:28

Available Files

Data

1A_Stroma.tiff 1A_Stroma.tiff 1A_Stroma.tiff Visible to: Anyone Content type: Data Metadata Revision: 3 Mime-Type: image/tiff License: Creative Commons: Attribution 4.0 File size: 428MB

1A_Tumour_Core.tiff 1A_Tumour_Core.tiff 1A_Tumour_Core.tiff Visible to: Anyone Content type: Data Metadata Revision: 4 Mime-Type: image/tiff License: Creative Commons: Attribution 4.0 File size: 370MB

1B_Stroma.tiff 1B_Stroma.tiff 1B_Stroma.tiff Visible to: Anyone Content type: Data Metadata Revision: 3 Mime-Type: image/tiff License: Creative Commons: Attribution 4.0 File size: 327MB

1B_Tumour_Core.tiff 1B_Tumour_Core.tiff 1B_Tumour_Core.tiff Visible to: Anyone Content type: Data Metadata Revision: 3 Mime-Type: image/tiff License: Creative Commons: Attribution 4.0 File size: 427MB

RCC_Files.zip RCC_Files.zip RCC_Files.zip Visible to: Anyone Content type: Data Metadata Revision: 3 Mime-Type: application/zip License: Creative Commons: Attribution 4.0 File size: 101kB

TNBC-negprobe-n ... -all-GeoMx.xlsx TNBC-negprobe-n ... -all-GeoMx.xlsx TNBC-negprobe-n ... -all-GeoMx.xlsx Visible to: Anyone Content type: Data Metadata Revision: 3 Mime-Type: application/vnd.openxmlformats-officedocument.spreadsheetml.sheet License: Creative Commons: Attribution 4.0 File size: 206kB

TNBC-raw-data-GeoMx.xlsx TNBC-raw-data-GeoMx.xlsx TNBC-raw-data-GeoMx.xlsx Visible to: Anyone Content type: Data Metadata Revision: 3 Mime-Type: application/vnd.openxmlformats-officedocument.spreadsheetml.sheet License: Creative Commons: Attribution 4.0 File size: 272kB

Read me

Readme-summary- ... NBC-dataset.txt Readme-summary- ... NBC-dataset.txt Readme-summary- ... NBC-dataset.txt Visible to: Anyone Content type: Read me Metadata Revision: 4 Mime-Type: text/plain License: Creative Commons: Attribution 4.0 File size: 1kB

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