TLR7-induced murine inflammation results in a global neuroinflammatory response driving neural circuit-specific transcriptomic changes

Gardner-Stephen, K., Carvajal Quisilema, R., Andrianova, L., McGonigal, R. , Sharma, D., Barrie, J., Saathoff, M., Cole, J., Jamieson, N. , Craig, M. T. and Cavanagh, J. (2025) TLR7-induced murine inflammation results in a global neuroinflammatory response driving neural circuit-specific transcriptomic changes. [Data Collection]

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Collection description

Spatial transcriptomics (CosMx) data profiling of brains of wild-type C57BL/6J female mice (8 weeks old) undergoing a 3-day topical application of control or Aldara (Imiquimod-containing cream) cream to induce neuroinflammation.

College / School: College of Medical Veterinary and Life Sciences > School of Infection and Immunity
College of Medical Veterinary and Life Sciences > School of Psychology and Neuroscience
Date Deposited: 03 Nov 2025 11:44
URI: https://researchdata.gla.ac.uk/id/eprint/2076

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Gardner-Stephen, K., Carvajal Quisilema, R., Andrianova, L., McGonigal, R. , Sharma, D., Barrie, J., Saathoff, M., Cole, J., Jamieson, N. , Craig, M. T. and Cavanagh, J. (2025); TLR7-induced murine inflammation results in a global neuroinflammatory response driving neural circuit-specific transcriptomic changes

University of Glasgow

DOI: 10.5525/gla.researchdata.2076

Retrieved: 2025-11-04

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