Raw data on the development of a synthetic in vitro bone marrow niche, the development of a combined CRISPR-CAR T-cell therapy, and the model niche being used to test CRISPR-CAR T-cell therapy for acute myeloid leukaemia. Please note that the data files associated with this record are only available for reuse to projects which have been granted ethical approval. Please use the 'Request Data' button to start the access process.