This readme file was generated on 2026-01-05 by Eva Christina Schliewert



GENERAL INFORMATION

Title of Dataset: Experimental infection with African horse sickness virus results in an overt consumptive coagulopathy

Author/Principal Investigator Information
Name: Eva Christina Schliewert
ORCID:https://orcid.org/0000-0003-3763-8203
Institution: University of Glasgow, UK/ University of Pretoria, SA
Email:tine.schliewert@glasgow.ac.uk

Author/Associate or Co-investigator Information
Name:Amelia Goddard
ORCID:https://orcid.org/0000-0002-8415-4802
Institution: University of Pretoria, SA
Email:amelia.goddard@up.ac.za

Author/Associate or Co-investigator Information
Name:Emma Hooijberg
ORCID:https://orcid.org/0000-0002-4367-799X
Institution: Nationwide Laboratories, UK/ University of Pretoria, SA
Email:emma.hooijberg@up.ac.za


- Date of data collection: November/December 2020
- Geographic location of data collection: Pretoria, South Africa
- Information about funding sources that supported the collection of the data: n/a


SHARING/ACCESS INFORMATION

- Recommended citation for this dataset: https://doi.org/10.5525/gla.researchdata.2128.

DATA & FILE OVERVIEW

File List: 
AHS Hemostasis
AHS TEGs
AHS Vcurves

Samples obtained prior to infection with African horse sickness virus, then every 24 hours until humane euthanasia

- Relationship between files, if important: n/a
- Additional related data collected that was not included in the current data package:
- Are there multiple versions of the dataset? n/a
	


METHODOLOGICAL INFORMATION

Description of methods used for collection/generation of data:
This was a prospective, descriptive study where four horses were experimentally infected with AHSV. Blood samples were obtained before infection, then every 24 hours until humane euthanasia. Haematology and thromboelastography (TEG) was performed and prothrombin time (PT), activated partial thromboplastin time (aPTT), fibrinogen and D-dimer concentrations, as well as activities of antithrombin (AT) and coagulation factors II, VII, VIII, X, and XII were measured.



Instrument- or software-specific information needed to interpret the data:
Microsoft Excel



DATA-SPECIFIC INFORMATION FOR: AHS hemostasis

- Number of variables: 13
- Number of cases/rows: 4/10
- Variable List: prothrombin time (PT, sec); activated partial thromboplastin time (aPTT, sec); D-Dimer (ng/ml); Firinogen (fibr, g/L); Factor II (FII, %); Factor V (FV, %);Factor VII (FVII, %);Factor X (X, %);-Factor XII (FXII, %); Plasminogen (absolut/%); Plasminogen inhibitor (absolut/%)

DATA-SPECIFIC INFORMATION FOR: AHS TEGS

- Number of variables: 10
- Number of cases/rows: 4/10
- Variable List: reaction time (R), clotting time (K), α-angle, maximum amplitude (MA), global clot strength (G), percent of clot lysis at 30 and 60 minutes (LY30 and LY60) and whole blood clot lysis index at 30 and 60 minutes (CL30 and CL60)

DATA-SPECIFIC INFORMATION FOR: AHS TEGS

- Number of variables: 10
- Number of cases/rows: 4/10
- Variable List: maximum rate of thrombus generation (MRTG), time to maximum rate of thrombus generation (TMRTG), thrombus generation (TG), maximum rate of lysis (MRL), time to maximum rate of lysis (TMRL) and lysis