The data in this archive is related to the paper 'Palmitoylation of the pore-forming subunit of Ca(v)1.2 controls channel voltage sensitivity and calcium transients in cardiac myocytes'. Each file contains the raw data underlying one panel of each figure in the publication, with a naming convention for the files that matches the figure they are related to. Microsoft Excel files contain: Quantitative data (band intensities) from analysis of images of western immunoblots Quantitative data (current values and voltages) from analysis of electrophysiological recordings of current records Quantitative data from analysis of intracellular calcium concentrations in cardiac myocytes Quantitative modelling of action potentials and calcium transients Microsoft Powerpoint files contain original uncropped images of western immunoblots. The area of each immunoblot presented in the manuscript is delineated with a dotted line. Python code describes a model of cardiac calcium handling and electrophysiology, implemented in the myokit ide