Dear Reader, Thank you for making it this far and accessing the underlying data associated with Sugrue and Wickenhagen et al., 2022. Additional underlying data are available as follows: The underlying code is openly available (http://doi.org/10.5281/zenodo.6780406) and is particularly pertinent to Figure 4, Figure 5 and Figure S3. The sequencing data has been deposited in the Sequence Read Archive (SRA), accession PRJNA858634 (https://www.ncbi.nlm.nih.gov/sra/PRJNA858634). Any problems, please contact Sam Wilson (sam.wilson@glasgow.ac.uk) in the first instance and he will direct you to the relevant person. Warm regards from Glasgow, Sam The Apparent Interferon Resistance of Transmitted HIV-1 is Possibly a Consequence of Enhanced Replicative Fitness Elena Sugrue1¶, Arthur Wickenhagen1¶, Nardus Mollentze1,2, Muhamad Afiq Aziz1,3, Vattipally B Sreenu1, Sven Truxa1,4, Lily Tong1, Ana da Silva Filipe1, David L Robertson1, Joseph Hughes1, Suzannah J Rihn1*, Sam J Wilson1* 1MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, United Kingdom 2School of Biodiversity, One Health & Veterinary Medicine, University of Glasgow, Glasgow, United Kingdom 3Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia 4Division of Systems Immunology and Single Cell Biology, German Cancer Research Center, Heidelberg ¶These authors contributed equally to this work *To whom correspondence should be addressed (suzannah.rihn@glasgow.ac.uk; sam.wilson@glasgow.ac.uk)