Clark, J. S., Romiti, F., Hogg, K., F., Hamid, M. H. S. A., Richter, S. C., Boyer, A., Redman, J. C. and Farrugia, L. J. (2015) Synthesis of cyclopropyl-substituted furans by Brønsted acid promoted cascade reactions. [Data Collection]
Collection description
Chloroacetic acid promotes an efficient and diastereoselective intramolecular cascade reaction of electron-deficient ynenones to deliver products featuring a 2,3,5-trisubstituted furan bearing a fused cyclopropyl substituent at the 5-position. Synthetically relevant polycyclic building blocks featuring rings of various sizes and heteroatoms have been synthesized in high yield using this mild acid-catalyzed reaction.
| Keywords: | Crystal structure |
|---|---|
| College / School: | College of Science and Engineering > School of Chemistry |
| Date Deposited: | 14 May 2015 10:27 |
| Enlighten Publications URL: | http://eprints.gla.ac.uk/106036/ |
| Funder's Name: | Engineering & Physical Sciences Research Council (EPSRC) |
| URI: | http://researchdata.gla.ac.uk/id/eprint/166 |
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